1993

 

 

  • Synaptobrevin, syntaxin, and SNAP-25 are identified as proteins essential for synaptic vesicle transmission.
  • Synaptobrevin is found to reside on the vesicle, whereas syntaxin and SNAP-25 reside on the plasma membrane.
  • Syntaxin and SNAP-25 are identified as molecular targets of BoNT-C and BoNT-A, respectively.